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Въпрос на ген ли е това дали сме слаби или дебели?
Проучванията сочат, че около 25-30% от предразположенността човек да бъде със свръхтегло или затлъстяване, се дължи на гените. Известно е т.нар моногенно и полигенно затлъстяване. Много хубаво и прекрасно би било да имаме само моногенни форми на затлъстяване, което означава един ген-една болест. Съществуват такива моногенни форми, но те се проявяват обичайно в детска възраст, самостоятелно или като част от изявата на определени генетични синдроми. Социално значимите форми на затлъстяване обаче се асоциират най-вече с полигенната форма, т.е. много гени и по- точно определени техни полиморфизми (варианти на даден ген) са отговорни за това човек да развие затлъстяване. Всички ние носим гени на затлъстяването, но това не означава непременно да сме със свръхтегло. Дори човек да е носител на определена група от полиморфизми, определящи риска от затлъстяване, в крайна сметка факторите на околната среда остават предопределящи дали този човек ще отключи затлъстяването, или не. Тоест, ако човек има гени, които касаят възможността той да има затлъстяване, но води здравословен начин на живот, физически активен е и се храни адекватно, рискът той да затлъстее се намалява. Както е възможно и обратното: човек, който има комбинация от протективни и/или непредразполагащи към свръхтегло и затлъстяване полиморфизми, но той се прехранва и има много ниски нива на физическа активност, високи нива на стрес, нарушен режим на труд и почивка, и прочие предразполагащи фактори, в крайна сметка също би могъл да отключи затлъстяване.
В такъв случай можем ли въобще да се доверим на ДНК тестовете, ВЕГА тестовете и храненето спрямо кръвната група?
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20.02.2023 | 18:36
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